2. Metabolic Enzyme/Protease
  3. ANGPTL
  4. Zodasiran sodium

Zodasiran sodium  (Synonyms: ARO-ANG3 sodium)

目录号: HY-177671A
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Zodasiran sodium 是一种靶向肝脏中 ANGPTL3 蛋白的 siRNA，被用于高血脂症的研究。

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RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Gm-Cm-Um-Cm-Am-Am-Cm-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Um-Um-Gm-Am-Um-Cm-Am-Gm-Um-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate] sodium salt, complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Cm-sp-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)G-sp-Cm) sodium salt (1:23:1:20)

Zodasiran sodium Chemical Structure

CAS No. : 2232918-74-8

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Zodasiran sodium 相关抗体

Top Publications Citing Use of Products

查看 ANGPTL 亚型特异性产品:

查看所有亚型
ANGPTL3 ANGPTL4 ANGPTL8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zodasiran sodium is a siRNA targeted to ANGPTL3 in the liver.

分子量

16509.90

Formula

C491H603F13N162Na43O309P43S7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Zodasiran sodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zodasiran2232918-74-8ARO-ANG3ANGPTLAngiopoietin-like proteinInhibitorinhibitorinhibit

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