1H-Indol-5-amine  (Synonyms: 5-氨基吲哚; 5-Aminoindole)

1H-Indol-5-amine (5-Aminoindole) is an organic compound containing an indole ring structure and belongs to the class of indole derivatives. 1H-Indol-5-amine can serve as a key intermediate for the synthesis of other active compounds^[1][2].

1H-Indol-5-amine 可与 Aromatic aldehydes、Tert-butyl 2,4-dioxopiperidine-1-carboxylate 在无催化剂条件下于乙醇中回流发生三组分反应，生成 11-aryl-3H-indolo[5,4-b][1,6]naphthyridine 衍生物^[1]。
1H-Indol-5-amine 是一种用于制备 AI-Sepharose 疏水电荷诱导色谱介质的配体，可通过疏水作用和 pH 诱导的电荷排斥实现蛋白质吸附与洗脱，具备蛋白纯化应用潜力^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

132.17

C₈H₈N₂

5192-03-0

固体

Light brown to black

1H-吲哚-5-氨基；5-氨基吲哚

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Li C, et al., Combinatorial synthesis of fused tetracyclic heterocycles containing [1,6]naphthyridine derivatives under catalyst free conditions. ACS Comb Sci. 2013 May 13;15(5):267-72.  [Content Brief]

  [2]. Zhao G, et al., 5-Aminoindole, a new ligand for hydrophobic charge induction chromatography. J Chromatogr A. 2008 Nov 21;1211(1-2):90-8.   [Content Brief]