1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 2'-C-Ethynyluridine

2'-C-Ethynyluridine  (Synonyms: 2'-C-乙炔基尿苷)

目录号: HY-W020361
产品使用指南

2'-C-Ethynyluridine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成,诱导细胞凋亡 (apoptosis) 等。2'-C-Ethynyluridine 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

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2'-C-Ethynyluridine Chemical Structure

2'-C-Ethynyluridine Chemical Structure

CAS No. : 188413-98-1

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100 mg ¥3650
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2'-C-Ethynyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2'-C-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

分子量

268.22

Formula

C11H12N2O6

CAS 号
中文名称

2'-C-乙炔基尿苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2'-C-Ethynyluridine 相关分类

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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2'-C-Ethynyluridine
目录号:
HY-W020361
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