1. Metabolic Enzyme/Protease
  2. Tyrosinase Endogenous Metabolite
  3. 2-Ketoglutaric acid Sodium

2-Ketoglutaric acid Sodium  (Synonyms: Alpha-Ketoglutaric acid Sodium)

目录号: HY-W013636AG
产品使用指南 技术支持

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) (GMP) 是 GMP 级别的 2-Ketoglutaric acid Sodium (HY-W013636A)。GMP 级别的小分子可用做细胞疗法中的辅助试剂。2-Ketoglutaric acid Sodium 是 Krebs 循环中 ATP 或 GTP 产生的中间体。2-Ketoglutaric acid Sodium 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid Sodium 是酪氨酸酶 (tyrosinase) 的可逆抑制剂 (IC50=15 mM)。

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2-Ketoglutaric acid Sodium Chemical Structure

2-Ketoglutaric acid Sodium Chemical Structure

CAS No. : 22202-68-2

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Other Forms of 2-Ketoglutaric acid Sodium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM)[1].

体外研究
(In Vitro)

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) 具有其他生理功能,包括降低肺部形成的氨水平和一般氨解毒、防止脂质过氧化和防止氰化物中毒的神经保护作用[1]
2-Ketoglutaric acid Sodium (GMP) 是合成氨基酸和核苷酸的前体[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

168.08

同用名

Alpha-Ketoglutaric acid Sodium

Formula

C5H5NaO5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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