2. Membrane Transporter/Ion Channel
  3. Monoamine Transporter
  4. (2S,3S,11bR)-Dihydrotetrabenazine

(2S,3S,11bR)-Dihydrotetrabenazine  (Synonyms: (2S,3S,11bR)-DHTBZ)

目录号: HY-141554A
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(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) 是一种高选择性的囊泡单胺转运体 2 (VMAT2) 抑制剂，Ki 值为 593 nM。(2S,3S,11bR)-Dihydrotetrabenazine 抑制多巴胺和 5-羟色胺等单胺类神经递质的囊泡转运，减少突触间隙单胺类递质释放。(2S,3S,11bR)-Dihydrotetrabenazine 有望用于亨廷顿舞蹈症及其他运动亢进性疾病的研究。

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(2S,3S,11bR)-Dihydrotetrabenazine

(2S,3S,11bR)-Dihydrotetrabenazine Chemical Structure

CAS No. : 862377-27-3

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Other Forms of (2S,3S,11bR)-Dihydrotetrabenazine:

(2S,3S,11bR)-Dihydrotetrabenazine 相关抗体

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生物活性

(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. (2S,3S,11bR)-Dihydrotetrabenazine inhibits vesicular transport of monoamine neurotransmitters like dopamine and serotonin, reducing their synaptic release. (2S,3S,11bR)-Dihydrotetrabenazine is promising for research of Huntington's chorea and other hyperkinetic disorders[1].

分子量

319.44

Formula

C19H29NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(2S,3S,11bR)-Dihydrotetrabenazine 相关分类

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Keywords:

(2S,3S,11bR)-Dihydrotetrabenazine862377-27-3(2S,3S,11bR)-DHTBZMonoamine TransporterVMAT2vesicular transportHuntington's choreaInhibitorinhibitorinhibit

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