2. Metabolic Enzyme/Protease PROTAC GPCR/G Protein
  3. PROTAC Linkers Endogenous Metabolite Leukotriene Receptor
  4. Leukotriene B4

Leukotriene B4  (Synonyms: LTB4; 5(S),12(R)-DiHETE)

目录号: HY-107608 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Leukotriene B4 (LTB4) 是白细胞最有效的化学诱导剂和激活剂之一，参与多种炎症性疾病。Leukotriene B4 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

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Leukotriene B4 Chemical Structure

Leukotriene B4 Chemical Structure

CAS No. : 71160-24-2

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规格 价格 是否有货 数量
25 μg (297.2 µM * 250 μL in Ethanol) ￥5850
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Other Forms of Leukotriene B4:

Leukotriene B4 相关抗体

Top Publications Citing Use of Products

查看 PROTAC Linkers 亚型特异性产品:

查看所有亚型
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3].

IC50 & Target

Alkyl-Chain

 

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Leukotriene B4 induces recruitment and activation of neutrophils, monocytes and eosinophils. It also stimulates the production of a number of proinflammatory cytokines and mediators indicating an ability to augment and prolong tissue inflammation[2].
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Leukotriene B4 相关抗体:
Clinical Trial
分子量

336.47

Formula

C20H32O4
CAS 号
性状

液体

颜色

Colorless to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: ≥98.0%

COA (160 KB)

产品使用指南 (1538 KB)
参考文献

Leukotriene B4 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leukotriene B471160-24-2LTB4 5(S),12(R)-DiHETELeukotriene B 4Leukotriene B-4LTB 4LTB-4PROTAC LinkersEndogenous MetaboliteLeukotriene ReceptorInhibitorinhibitorinhibit

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