2. GPCR/G Protein
  3. G protein-coupled Bile Acid Receptor 1
  4. 5β-Cholestane-3α,7α,12α,25-tetrol

5β-Cholestane-3α,7α,12α,25-tetrol  (Synonyms: 3α,7α,12α,25-Tetrahydroxycoprostane)

目录号: HY-171949
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5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) 是一种胆汁酸醇。5β-Cholestane-3α,7α,12α,25-tetrol 是 GPBAR1 (别名TGR5) 的激活剂 (EC50: 1.36 μM)。5β-Cholestane-3α,7α,12α,25-tetrol 是脑腱黄瘤病 (CTX) 患者中的主要胆汁醇疾病标志物。

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5β-Cholestane-3α,7α,12α,25-tetrol

5β-Cholestane-3α,7α,12α,25-tetrol Chemical Structure

CAS No. : 18866-87-0

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5β-Cholestane-3α,7α,12α,25-tetrol 相关抗体

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生物活性

5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5) activator (EC50: 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX)[1][2].

分子量

436.67

Formula

C27H48O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5β-Cholestane-3α,7α,12α,25-tetrol 相关分类

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Keywords:

5β-Cholestane-3α,7α,12α,25-tetrol18866-87-03α,7α,12α,25-TetrahydroxycoprostaneG protein-coupled Bile Acid Receptor 1G-protein coupled receptor 19GPCR19TGR5GPBAR1Cerebrotendinous xanthomatosisBile alcoholInhibitorinhibitorinhibit

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