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  3. Calmodulin-Dependent Protein Kinase II (290-309)

Calmodulin-Dependent Protein Kinase II (290-309) 

目录号: HY-P1479
产品使用指南

Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗剂, 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。

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Calmodulin-Dependent Protein Kinase II (290-309) Chemical Structure

Calmodulin-Dependent Protein Kinase II (290-309) Chemical Structure

CAS No. : 115044-69-4

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Calmodulin-Dependent Protein Kinase II (290-309) 的其他形式现货产品:

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  • 生物活性

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生物活性

Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

IC50 & Target

IC50: 52 nM (calmodulin-dependent protein kinase II)[1]

体外研究
(In Vitro)

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2273.83

Formula

C103H185N31O24S

CAS 号
Sequence

Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala

Sequence Shortening

LKKFNARRKLKGAILTTMLA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Calmodulin-Dependent Protein Kinase II (290-309) 相关分类

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产品名称:
Calmodulin-Dependent Protein Kinase II (290-309)
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HY-P1479
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