2. 多肽产品
  3. 多肽及其衍生物
  4. 激素肽与神经肽
  5. Katacalcin TFA

Katacalcin TFA  (Synonyms: PDN 21 TFA)

目录号: HY-P0149A 纯度: 99.55%
COA 产品使用指南 技术支持

Katacalcin TFA (PDN 21 TFA) 是一种有效的具有降低血钙效应的多肽激素。

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Custom Peptide Synthesis

Katacalcin TFA Chemical Structure

Katacalcin TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥800
In-stock
5 mg ￥2000
In-stock
10 mg ￥3200
In-stock
25 mg ￥4800
In-stock
50 mg 现货 询价
100 mg 现货 询价
200 mg   询价  
500 mg   询价  

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Customer Review

Other Forms of Katacalcin TFA:

Katacalcin TFA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Katacalcin TFA (PDN 21 TFA) is a potent plasma calcium-lowering peptide[1].

体外研究
(In Vitro)

Katacalcin 是一种有效的血浆降钙肽。Katacalcin 属于降钙素家族，通过促进这些离子在骨骼中的结合，导致血液中钙和磷酸盐水平快速但短暂的下降[1]。Katacalcin (KC) 属于由 calc-1 基因编码的一个多肽小家族，还包括降钙素 (CT) 和原降钙素 NH2-末端裂解肽 (N-ProCT)。Katacalcin 预处理导致浓度依赖性降低，浓度在 1 amol/升和 10 fmol/升之间，并且是比 CT 或降钙素原 (PCT) 更有效的 fMLP 诱导的趋化性抑制剂。Katacalcin 使 CD14+ 外周血单核细胞 (PBMC) 不仅对 N-甲酰-Met-Leu-Phe (fMLP) 趋化而且对趋化因子家族的其他引诱剂 (异源失活) 以及对 PCT 和 CT。用 Katacalcin 预处理 CD14+ PBMC 也会使随后对 Katacalcin 本身的趋化作用失活。Katacalcin 在原子摩尔浓度到微摩尔浓度范围内引起 CD14+ PBMC 的浓度依赖性迁移，并使引诱剂诱导的趋化性失活。Katacalcin 通过涉及蛋白激酶 A 依赖性 cAMP 通路的信号事件调节人 CD14+ PBMC 迁移[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Katacalcin TFA 相关抗体:
分子量

2550.62

Formula

C99H155F3N34O38S2
性状

固体

颜色

White to off-white

Sequence

Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn
Sequence Shortening

DMSSDLERDHRPHVSMPQNAN
中文名称

钙抑肽三氟乙酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料

纯度: 99.55%

COA (278 KB) LCMS (104 KB) 元素分析报告 (203 KB)

产品使用指南 (1538 KB)
参考文献

Katacalcin TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KatacalcinPDN 21钙抑肽三氟乙酸盐PDN21PDN-21OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
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