1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 已知活性化合物库
  5. 生物活性化合物库 Plus
生物活性化合物库 Plus - Bioactive Compound Library Plus

Cat. No.: HY-L001P

生物活性化合物是一类能够在机体内引起一定生物学效应的物质的总称,是小分子药物的主要来源。这类化合物一般比较容易透过细胞膜,作用于细胞内特定的靶蛋白,调控细胞内信号通路,进而引起细胞表型的一些变化。

MCE 收录了 22628 种具有明确报道的、活性已知、靶点明确的小分子化合物,包括天然产物、新型化合物、已上市化合物及处于临床期化合物等,是信号通路研究、新药研发、老药新用等研究的有力工具。

生物活性库 Plus 是对 MCE 生物活性库 (HY-L001) 的进一步补充,添加了一些低溶液稳定性和溶解度的化合物 (Part B) 及新型,稀有及 MCE 特有的一些化合物 (Part C),具有更强的筛选能力。补充的化合物均以粉末形式提供。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 生物活性化合物库 Plus,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,18455 个产品以 10 mM 浓度提供,298 个产品以 2 mM 浓度提供,67 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +

Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Widely used in the research focus areas such as Cancer, Stem Cell, Neuronal Signaling, Immunity, and more.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

  Part A Part B Part C
Number 18820 1545 2263
Feature General compounds (HY-L001) Compounds with low solubility or stability Novel, rare or exclusive compounds
Package Solution (10 mM) or solid (1 mg) Only solid (1 mg) Only solid (1 mg)

产品详情

Product Details

Formulation:

A collection of 22628 bioactive compounds supplied as pre-dissolved Solutions or Solid
Solution: 18455 compounds supplied in 10 mM solution, 298 compounds supplied in 2 mM solution, 67 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

Fungal (405)

NF-κB (285)

CDK (279)

HIV (275)

PROTACs (227)

COX (226)

PI3K (221)

EGFR (214)

iGluR (173)

VEGFR (170)

mAChR (163)

Akt (154)

HDAC (154)

JAK (138)

STAT (133)

Ras (131)

PPAR (129)

MMP (126)

Caspase (124)

HCV (123)

mGluR (123)

ERK (121)

PARP (118)

nAChR (114)

mTOR (111)

Wnt (99)

PKC (98)

FGFR (97)

HSP (95)

FLT3 (93)

PDGFR (89)

AMPK (88)

HBV (88)

GSK-3 (83)

Src (81)

HSV (79)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Bioactive Compound Library Plus
    目录号:
    HY-L001P
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