1. Metabolic Enzyme/Protease
  2. Xanthine Oxidase Endogenous Metabolite
  3. Phytic acid

Phytic acid  (Synonyms: 植酸; Inositol hexaphosphate; SNF472 free acid)

目录号: HY-N0814 纯度: ≥95.0%
COA 产品使用指南

Phytic acid (Inositol hexaphosphate) 是种子和谷粒的磷储存化合物。Phytic acid 被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是锌,钙,铁和蛋白质残留物。Phytic acid 抑制超氧化物来源黄嘌呤氧化酶 (XO) 并具有抗氧化,神经保护以及抗炎作用。

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Phytic acid Chemical Structure

Phytic acid Chemical Structure

CAS No. : 83-86-3

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规格 价格 是否有货 数量
250 mg (757.5 mM * 500 μL in Water) ¥500
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Other Forms of Phytic acid:

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4].

IC50 & Target

Xanthine oxidase[3]

体外研究
(In Vitro)

Phytic acid (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by phytic acid; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

660.04

Formula

C6H18O24P6

CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

植酸;肌醇六磷酸;肌醇六磷酸 (酯);环己六醇六磷酸

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (151.51 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

H2O 中的溶解度 : ≥ 30 mg/mL (45.45 mM)

* "≥" means soluble, but saturation unknown.

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥95.0%

参考文献
Animal Administration
[4]

Mice: MPTP (20 mg/kg/day, i.p.) is administrated for 5 days and animals are killed at 7 days later. Phytic acid (30 mg/kg/day, i.p.) or normalsaline is injected 4 days before MPTP administration and con-tinued until mice are killed, reaching a total treatment period of16 days[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.5151 mL 7.5753 mL 15.1506 mL 37.8765 mL
5 mM 0.3030 mL 1.5151 mL 3.0301 mL 7.5753 mL
10 mM 0.1515 mL 0.7575 mL 1.5151 mL 3.7876 mL
15 mM 0.1010 mL 0.5050 mL 1.0100 mL 2.5251 mL
20 mM 0.0758 mL 0.3788 mL 0.7575 mL 1.8938 mL
25 mM 0.0606 mL 0.3030 mL 0.6060 mL 1.5151 mL
30 mM 0.0505 mL 0.2525 mL 0.5050 mL 1.2625 mL
40 mM 0.0379 mL 0.1894 mL 0.3788 mL 0.9469 mL
DMSO 50 mM 0.0303 mL 0.1515 mL 0.3030 mL 0.7575 mL
60 mM 0.0253 mL 0.1263 mL 0.2525 mL 0.6313 mL
80 mM 0.0189 mL 0.0947 mL 0.1894 mL 0.4735 mL
100 mM 0.0152 mL 0.0758 mL 0.1515 mL 0.3788 mL

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phytic acid
目录号:
HY-N0814
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