1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Stearoylethanolamide

Stearoylethanolamide 是一种具有促细胞凋亡活性的内源性大麻素类化合物。

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Stearoylethanolamide

Stearoylethanolamide Chemical Structure

CAS No. : 111-57-9

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Other Forms of Stearoylethanolamide:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

IC50 & Target

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 GI50
129.5 μg/mL
Compound: 4b
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI/ADR-RES GI50
157.7 μg/mL
Compound: 4b
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
OVCAR-3 GI50
157.7 μg/mL
Compound: 4b
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
PC-3 GI50
75.6 μg/mL
Compound: 4b
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
U-251 GI50
116.9 μg/mL
Compound: 4b
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
体外研究
(In Vitro)

Stearoylethanolamide (SEA) 在人类、大鼠和小鼠大脑中的含量与内源性大麻素 anandamide (花生四烯酰乙醇胺;AEA) 相当。Stearoylethanolamide 是一种具有促细胞凋亡活性的内源性大麻素样化合物,其受 NO 的调节方式与报道的 AEA 相反[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

327.55

Formula

C20H41NO2

CAS 号
性状

固体

颜色

White to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 99.67%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Stearoylethanolamide
目录号:
HY-113015
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