1. Signaling Pathways
  2. Cytoskeleton
  3. Gap Junction Protein

Gap Junction Protein

Gap junction channels are essential in normal heart function and they assist in the mediated spread of electrical impulses that stimulate synchronized contraction (via an electrical syncytium) of cardiac tissues.

Gap junction (GJ) proteins play an important role in direct communication between cells of many tissue types. GJs are specialised intercellular membrane-spanning domains that allow the passage of small molecules including second messenger (e.g. c-AMP, inositol triphosphate) or ionic signals from one cell to another. GJ proteins and their long evolutionary history have permitted adaptation of gap junction intercellular communication (GJIC) with several important functions and multiple regulatory processes. Formation of GJIC is an essential mechanism in coordinating growth and development and tissue compartmentalization during embryonic development.

Gap Junction Protein 相关产品 (10):

Cat. No. Product Name Effect Purity
  • HY-106268A
    Larazotide acetate Inhibitor 99.68%
    Larazotide acetate 是一种合成肽,是一种紧密连接 (junction) 的调节剂。
  • HY-15204
    Tonabersat Modulator 99.68%
    Tonabersat 是一种 gap-junction 调节剂。
  • HY-10913A
    Danegaptide Hydrochloride Modulator 99.20%
    Danegaptide Hydrochloride (GAP-134 Hydrochloride) 是一种选择性的缝隙连接 (gap junction) 调节剂。
  • HY-P0139
    Gap 27 Inhibitor 98.34%
    Gap 27,connexin43拟肽,是间隙连接抑制剂。
  • HY-P1082
    Gap 26 Inhibitor 99.30%
    Gap 26 是一种连接蛋白 (connexin) 模拟肽,与 connexin 43 的 63-75 位氨基酸残基相对应,为 gap junction 的阻滞剂。
  • HY-117275
    Meclofenamic acid Inhibitor
    Meclofenamic acid是一种非甾体抗炎药 (NSAID),被批准用于关节炎 (骨关节炎和类风湿性关节炎)、镇痛 (轻度至中度疼痛)、痛经和严重月经失血(月经过多)。Meclofenamic acid是一种非选择性的 gap-junction 阻断剂,是一种高选择性的脂肪和肥胖相关酶 (FTO) 抑制剂。
  • HY-B1320
    Meclofenamate sodium Inhibitor
    Meclofenamate sodium (Meclofenamic acid sodium) 是一种非甾体抗炎药 (NSAID),被批准用于关节炎 (骨关节炎和类风湿性关节炎)、镇痛 (轻度至中度疼痛)、痛经和严重月经失血 (月经过多)。Meclofenamate sodium (Meclofenamic acid sodium) 是一种非选择性的 gap-junction 阻断剂,是一种高选择性的脂肪和肥胖相关酶 (FTO) 抑制剂。
  • HY-114426A
    AT-1002 TFA Modulator 99.84%
    AT-1002 TFA 是一种 6 聚体合成肽,是一种紧密连接 (junction) 的调节剂和吸收增强剂。
  • HY-10913
    Danegaptide Modulator
    Danegaptide (GAP-134) 是修饰的二肽,是第二代口服生物相容性的间隙连接调节剂。
  • HY-114426
    AT-1002 Modulator
    AT-1002 是一种 6 聚体合成肽,是一种紧密连接 (junction) 的调节剂和吸收增强剂。
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