1. Epigenetics Protein Tyrosine Kinase/RTK JAK/STAT Signaling Stem Cell/Wnt
  2. JAK
  3. (3S,4R)-Tofacitinib

(3S,4R)-Tofacitinib  (Synonyms: (3S,4R)-托法替尼)

目录号: HY-40354B
产品使用指南

(3S,4R)-Tofacitinib 是 Tofacitinib 的低活性异构体。Tofacitinib 抑制 JAK3,IC50 为 1 nM。

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(3S,4R)-Tofacitinib Chemical Structure

(3S,4R)-Tofacitinib Chemical Structure

CAS No. : 1092578-48-7

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  • 生物活性

  • 纯度 & 产品资料

生物活性

(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

分子量

312.37

Formula

C16H20N6O

CAS 号
中文名称

(3S,4R)-托法替尼

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(3S,4R)-Tofacitinib
目录号:
HY-40354B
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