1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. A-77636 hydrochloride

A-77636 hydrochloride 

目录号: HY-103416 纯度: ≥98.0%
COA 产品使用指南

A-77636 hydrochloride 是一种具有口服活性的、选择性的和长效多巴胺 D1 受体激动剂 (pKi=7.40; Ki=39.8 nM),具有抗帕金森病活性。A-77636 hydrochloride 对多巴胺 D2 受体无功能活性。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

A-77636 hydrochloride Chemical Structure

A-77636 hydrochloride Chemical Structure

CAS No. : 145307-34-2

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥1500
In-stock
5 mg ¥3500
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of A-77636 hydrochloride:

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor[1][2].

IC50 & Target

D2 Receptor

 

体内研究
(In Vivo)

A-77636 hydrochloride (0.1-1 mg/kg) 对食物摄入有抑制作用,减少了进餐量和持续时间[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male hooded rat[1]
Dosage: 0.1, 0.3 and 1.0 mg/kg
Administration: S.c.
Result: Exerted a suppressant effect on food intake, due principally to a reduction in meal size and duration.
分子量

365.89

Formula

C20H28ClNO3

CAS 号
性状

固体

颜色

Brown to black

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥98.0%

参考文献

A-77636 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
A-77636 hydrochloride
目录号:
HY-103416
需求量: