Dopamine Receptor Inhibitors

Dopamine Receptor

D₁ Receptor

D₂ Receptor

D₃ Receptor

D₄ Receptor

D₅ Receptor

Dopamine Receptor Inhibitors, Agonists, Antagonists & Modulators

Product Name	Dopamine Receptor	D₁ Receptor	D₂ Receptor	D₃ Receptor	D₄ Receptor	D₅ Receptor	Purity
SKF 81297		D₁ Receptor					99.86%
SCH-23390 hydrochloride		D₁ Receptor, Ki: 0.2 nM				D₅ Receptor, Ki: 0.3 nM	99.91%
Haloperidol			D₂ Receptor				99.65%
SKF 38393 hydrochloride		D₁ Receptor					99.49%
Clozapine			D₂ Receptor, Ki: 75 nM (Antagonist)				99.97%
Cabergoline			D₂ Receptor	D₃ Receptor			99.86%
Risperidone			D₂ Receptor, Ki: 5.9 nM				99.92%
Olanzapine	Dopamine Receptor						99.83%
Aripiprazole			D₂ Receptor	D₃ Receptor	D₄ Receptor		99.95%
Brexpiprazole			D_2L Receptor, Ki: 0.3 nM				99.85%
Flunarizine dihydrochloride			D₂ Receptor				99.87%
Sulpiride			D₂ Receptor	D₃ Receptor			99.75%
WAY-100635 maleate					D₄ Receptor		99.89%
Lurasidone			D₂ Receptor, IC₅₀: 1.68 nM				99.90%
Nuciferine			D₂ Receptor, EC₅₀: 64 nM		D₄ Receptor, EC₅₀: 2 μM	D₅ Receptor, EC₅₀: 2.6 μM	99.46%
Penfluridol			D₂ Receptor				99.93%
Perphenazine			D₂ Receptor, Ki: 0.56 nM	D₃ Receptor, Ki: 0.43 nM	D₄ Receptor, Ki: 28.5 nM		99.95%
Ritanserin			D₂ Receptor, IC₅₀: 70 nM				99.78%
Raclopride		D₁ Receptor, Ki: 18000 nM	D₂ Receptor, Ki: 1.8 nM	D₃ Receptor, Ki: 3.5 nM	D₄ Receptor, Ki: 2400 nM		99.72%
Paliperidone			D₂ Receptor				99.69%
WAY-100635					D₄ Receptor		99.32%
Benztropine mesylate			Human D₂ Receptor				99.92%
Pramipexole			D₂ Receptor, Ki: 3.9 nM	D₃ Receptor, Ki: 0.5 nM	D₄ Receptor, Ki: 1.3 nM		99.95%
SKF-82958 hydrobromide		D₁ Receptor					99.82%
Ziprasidone			Rat D₂ Receptor, Ki: 4.8 nM				99.81%
N-Methyldopamine hydrochloride		D₁ Receptor					99.03%
Domperidone			D₂ Receptor				99.79%
Dihydrexidine hydrochloride		D₁ Receptor, IC₅₀: 10 nM					99.21%
Cariprazine			D₂ Receptor, Ki: 0.49 nM	D₃ Receptor, Ki: 0.085 nM			99.83%
Pergolide mesylate		D₁ Receptor	D₂ Receptor				99.92%
Loxapine		Human D₁ Receptor	Human D₂ Receptor		Human D₄ Receptor		99.69%
Cariprazine hydrochloride			D₂ Receptor, Ki: 0.49 nM	D₃ Receptor, Ki: 0.085 nM			99.90%
Ropinirole hydrochloride			D₂ Receptor, Ki: 29 nM hD₂ Receptor, pEC₅₀: 7.4	hD₃ Receptor, pEC₅₀: 8.4	hD_4.4 Receptor, pEC₅₀: 6.8		99.85%
Pramipexole dihydrochloride			D₂ Receptor	D₃ Receptor	D₄ Receptor		≥98.0%
Lurasidone Hydrochloride			D₂ Receptor, IC₅₀: 1.68 nM				99.96%
Piribedil			D₂ Receptor	D₃ Receptor			99.33%
Sumanirole maleate			D₂ Receptor				≥99.0%
SKF-83566		D₁ Receptor				D₅ Receptor	99.86%
Rotigotine		D₁ Receptor, Ki: 83 nM	D₂ Receptor, Ki: 4-15 nM	D₃ Receptor, Ki: 0.71 nM	D₄ Receptor, Ki: 4-15 nM	D₅ Receptor, Ki: 4-15 nM	99.98%
Flupentixol dihydrochloride		D₁ Receptor	D₂ Receptor				99.73%
Paliperidone palmitate			D₂ Receptor				98.41%
Loxapine succinate		Human D₁ Receptor	Human D₂ Receptor		Human D₄ Receptor		99.81%
A68930 hydrochloride		D₁ Receptor					≥98.0%
Chlorprothixene hydrochloride		Human D₁ Receptor, Ki: 18 nM	Human D₂ Receptor, Ki: 2.96 nM	Human D₃ Receptor, Ki: 4.56 nM		Human D₅ Receptor, Ki: 9 nM	≥98.0%
PD-168077 maleate					D₄ Receptor		98.74%
Sarizotan			rD₂ Receptor, IC₅₀: 15.1 nM (rat) hD₂ Receptor, IC₅₀: 17 nM	D₃ Receptor, IC₅₀: 6.8 nM (human)	hD_4.2 Receptor, IC₅₀: 2.4 nM		98.74%
UNC9994 hydrochloride		D₁ Receptor, Ki: 4000 nM	D₂ Receptor, Ki: 79 nM	D₃ Receptor, Ki: 17 nM	D₄ Receptor, Ki: 138 nM		98.83%
Metoclopramide			D₂ Receptor, IC₅₀: 483 nM				99.94%
Chlorprothixene		Human D₁ Receptor, Ki: 18 nM	Human D₂ Receptor, Ki: 2.96 nM	Human D₃ Receptor, Ki: 4.56 nM		Human D₅ Receptor, Ki: 9 nM	99.61%
Pridopidine			D₂ Receptor				99.77%
LY3154207		D₁ Receptor					99.87%
SKF 81297 hydrobromide		D₁ Receptor					≥99.0%
Asenapine		D₁ Receptor, pKi: 8.9	D₂ Receptor, pKi: 8.9	D₃ Receptor, pKi: 9.4	D₄ Receptor, pKi: 9.0		99.93%
Ansofaxine hydrochloride	Dopamine Receptor, IC₅₀: 491 nM						99.87%
Ziprasidone hydrochloride monohydrate			Rat D₂ Receptor, Ki: 4.8 nM				99.74%
Thiethylperazine			D₂ Receptor				99.41%
SB-277011 hydrochloride				D₃ Receptor, Ki: 10.7-11.2 nM			98.54%
Blonanserin		D₁ Receptor, Ki: 1070 nM	D₂ Receptor, Ki: 0.142 nM	D₃ Receptor, Ki: 0.494 nM	D₄ Receptor, Ki: 150 nM		99.62%
Rotigotine Hydrochloride		D₁ Receptor, Ki: 83 nM	D₂ Receptor, Ki: 4-15 nM	D₃ Receptor, Ki: 0.71 nM	D₄ Receptor, Ki: 4-15 nM	D₅ Receptor, Ki: 4-15 nM	99.65%
Rotundine		D₁ Receptor, IC₅₀: 166 nM	D₂ Receptor, IC₅₀: 1400 nM	D₃ Receptor, IC₅₀: 3300 nM			99.87%
Ecopipam hydrochloride		D₁ Receptor, Ki: 1.2 nM	D₂ Receptor, Ki: 980 nM		D₄ Receptor, Ki: 5520 nM	D₅ Receptor, Ki: 2.0 nM	99.46%
Tiapride hydrochloride			D₂ Receptor, IC₅₀: 110-320 nM	D₃ Receptor, IC₅₀: 180 nM			99.86%
L-745870			D₂ Receptor, Ki: 960 nM	D₃ Receptor, Ki: 2300 nM	Human D₄ Receptor, Ki: 4.3 nM		99.92%
Itopride hydrochloride			D₂ Receptor				99.85%
Fluphenazine decanoate			D₂ Receptor				≥98.0%
Halopemide		D₁ Receptor	D₂ Receptor				99.65%
Ocaperidone			D₂ Receptor, Ki: 0.75 nM				99.93%
Iloperidone		Rat D₁ Receptor, Ki: 546 nM Human D₁ Receptor, Ki: 216 nM	Rat D₂ Receptor, Ki: 54 nM	Human D₃ Receptor, Ki: 7.1 nM	Human D₄ Receptor, Ki: 25 nM	Human D₅ Receptor, Ki: 319 nM	99.97%
Flunarizine			D₂ Receptor				99.87%
Pericyazine			D₂ Receptor				99.96%
Pramipexole dihydrochloride hydrate			D₂ Receptor, Ki: 3.9 nM	D₃ Receptor, Ki: 0.5 nM	D₄ Receptor, Ki: 1.3 nM		≥98.0%
(Rac)-Tavapadon		D₁ Receptor					99.87%
Xaliproden hydrochloride			D₂ Receptor, IC₅₀: 0.1-1 μM				98.57%
Thiethylperazine dimaleate			D₂ Receptor				99.72%
A-77636 hydrochloride			D₂ Receptor				≥98.0%
Brilaroxazine			D₂ Receptor	D₃ Receptor	D₄ Receptor		98.29%
Eticlopride hydrochloride			D₂ Receptor, Ki: 0.09 nM				99.45%
Talipexole dihydrochloride			D₂ Receptor				99.80%
Bromperidol			D₂ Receptor				98.48%
SKF 83959		D₁ Receptor, Ki: 1.18 nM	D₂ Receptor, Ki: 920 nM	D₃ Receptor, Ki: 399 nM		D₅ Receptor, Ki: 7.56 nM	98.93%
Desmethyl cariprazine			D₂ Receptor, Ki: 0.49 nM	D₃ Receptor, Ki: 0.085 nM			98.06%
Ecopipam hydrobromide		D₁ Receptor, Ki: 1.2 nM	D₂ Receptor, Ki: 980 nM		D₄ Receptor, Ki: 5520 nM	D₅ Receptor, Ki: 2.0 nM	≥99.0%
Brexpiprazole S-oxide-d₈			D₂ Receptor, Ki: 0.3 nM				98.72%
Promazine hydrochloride			D₂ Receptor				99.86%
UNC9995			D₂ Receptor				99.38%
Didesmethyl cariprazine			D₂ Receptor	D₃ Receptor			99.79%
SKF 83959 hydrobromide		D₁ Receptor, Ki: 1.18 nM	D₂ Receptor, Ki: 920 nM	D₃ Receptor, Ki: 399 nM		D₅ Receptor, Ki: 7.56 nM	99.86%
PF-06256142		Human D₁ Receptor, EC₅₀: 33 nM					98.70%
GSK163090			D₂ Receptor, pKi: 6.3	D₃ Receptor, pKi: 6.7			99.77%
Quinelorane dihydrochloride			D₂ Receptor	D₃ Receptor			≥99.0%
SKF 83822		Rat D₁ Receptor					98.66%
Spiramide		D₁ Receptor, Ki: 2530 nM	D₂ Receptor, Ki: 3 nM				99.23%
Acetophenazine dimaleate			D₂ Receptor				99.95%
Fananserin					D₄ Receptor, Ki: 2.93 nM		99.97%
(Rac)-PF-06256142		Human D₁ Receptor, EC₅₀: 107 nM					99.31%
Propionylpromazine hydrochloride			D₂ Receptor
NGB 2904				D₃ Receptor, Ki: 1.4 nM			≥98.0%
L-745870 hydrochloride			D₂ Receptor, Ki: 960 nM	D₃ Receptor, Ki: 2300 mM	Human D₄ Receptor, Ki: 4.3 nM		99.91%
Adoprazine			D₂ Receptor, pA2: 9.3 D₂ Receptor, pKi: 8.4	D₃ Receptor, pA2: 8.9 D₃ Receptor, pKi: 8.4	D₄ Receptor, pKi: 8.0		98.60%
ML417				D₃ Receptor, EC₅₀: 38 nM			99.50%
Naxagolide			D₂ Receptor				99.81%
Perospirone hydrochloride		D₁ Receptor, Ki: 41 nM	D₂ Receptor, Ki: 1.4 nM				99.94%
Olanzapine-d₃				D₃ Receptor			99.09%
ABT-724 trihydrochloride					D₄ Receptor		99.05%
CY 208-243		D₁ Receptor					99.98%
Buspirone			Dopamine D2 receptor				99.08%
(Rac)-Levomepromazine-d₃ hydrochloride				D₃ Receptor
Risperidone-d₄			D₂ Receptor				99.40%
Cariprazine-d₈				D₃ Receptor			99.51%
Zuclopenthixol dihydrochloride			D₂ Receptor				99.98%
Haloperidol-d₄			D₂ Receptor
Spiperone hydrochloride		D₁ Receptor, Ki: ~350 nM	D₂ Receptor, Ki: 0.06 nM	D₃ Receptor, Ki: 0.6 nM	D₄ Receptor, Ki: 0.08 nM	D₅ Receptor, Ki: ~3500 nM	99.10%
S-14506 hydrochloride			D₂ Receptor				99.92%
(S)-Amisulpride			D₂ Receptor	D₃ Receptor			99.75%
SKF-83566 hydrobromide		D₁ Receptor				D₅ Receptor
(-)-GSK598809 hydrochloride				D₃ Receptor			99.64%
cis-(Z)-Flupentixol dihydrochloride			D₂ Receptor, Ki: 0.38 nM
SKF-75670 hydrobromide		D₁ Receptor					99.83%
SB-277011 dihydrochloride				D₃ Receptor
ST-836 hydrochloride			D₂ Receptor, Ki: 132 nM	D₃ Receptor, Ki: 4.5 nM			98.11%
Risperidone hydrochloride			D₂ Receptor, Ki: 5.9 nM
Metoclopramide hydrochloride hydrate			D₂ Receptor, IC₅₀: 483 nM				99.94%
(Rac)-Rotigotine hydrochloride		D₁ Receptor, Ki: 83 nM	D₂ Receptor, Ki: 13.5 nM	D₃ Receptor, Ki: 0.71 nM	D₄ Receptor, Ki: 3.9-15 nM	D₅ Receptor, Ki: 5.4 nM	98.66%
Pardoprunox hydrochloride			D₂ Receptor, pEC₅₀: 8	D₃ Receptor, pEC₅₀: 9.2			98.24%
Ziprasidone hydrochloride			Rat D₂ Receptor, Ki: 4.8 nM
5-HT6/7 antagonist 1			D₂ Receptor
Propionylpromazine-d₆ hydrochloride			D₂ Receptor				99.78%
Blonanserin dihydrochloride		D₁ Receptor, Ki: 1070 nM	D₂ Receptor, Ki: 0.142 nM	D₃ Receptor, Ki: 0.494 nM	D₄ Receptor, Ki: 150 nM
Mesdopetam				D₃ Receptor
L-DOPA-2,5,6-d₃				D₃ Receptor			99.95%
Metoclopramide hydrochloride			D₂ Receptor, IC₅₀: 483 nM
Amisulpride-d₅ N-Oxide				D₃ Receptor
Iloperidone-d₃				D₃ Receptor
Cabergoline-d₅			D₂ Receptor	D₃ Receptor
Amisulpride-d₅				D₃ Receptor			98.83%
Paliperidone-d₄			D₂ Receptor
LE 300		Human D₁ Receptor, Ki: 1.9 nM				Human D₅ Receptor, Ki: 7.5 nM
Pergolide-d₇ mesylate			D₂ Receptor
Dopamine D3 receptor antagonist-2				D₃ Receptor, Ki: 2.16 nM
D4R antagonist-1					D₄ Receptor, IC₅₀: 6.87 μM
Mesulergine hydrochloride	Dopamine Receptor
Razpipadon		D₁ Receptor
Dopamine D4 receptor antagonist-1					hD_4.2 Receptor, Ki: 9.0 nM
Haloperidol-¹³C₆			D₂ Receptor
Blonanserin-d₈			D₂ Receptor
Dopamine D4 receptor ligand 2			D₂ Receptor, IC₅₀: >1000 nM		D₄ Receptor, IC₅₀: 0.057 nM
Agroclavine		D₁ Receptor
PD 119819	Dopamine Receptor
Dopamine D2 receptor agonist-3			D₂ Receptor, EC₅₀: 5 nM	D₃ Receptor, EC₅₀: >3.2 μM
SV 156			Human D₂ Receptor, Ki: 2.5 ± 0.4 nM	Human D₃ Receptor, Ki: 96.9 ± 4.3 nM	Human D₄ Receptor, Ki: 700 ± 56 nM
A-77636		Dopamine D1 receptor, EC₅₀: 1.1 nM Dopamine D1 receptor, Ki: 39.8 nM
FAUC 346				D₃ Receptor, EC₅₀: 1.5 nM			99.90%
Tau-aggregation-IN-1			D₂ Receptor	D₃ Receptor
SK609 hydrochloride				Dopamine D3 receptor, EC₅₀: 1109 nM
Fluphenazine decanoate dihydrochloride			D₂ Receptor
Ropinirole			D₂ Receptor, Ki: 29 nM hD₂ Receptor, pEC₅₀: 7.4	hD₃ Receptor, pEC₅₀: 8.4	hD_4.4 Receptor, pEC₅₀: 6.8
Dopamine D3 receptor ligand-1			D₂ Receptor, Ki: 715 nM	D₃ Receptor, Ki: 8 nM
OS-3-106				D₃ Receptor, Ki: 0.2 nM
D3R ligand 1				D₃ Receptor, Ki: 66 nM
NGB 2904 hydrochloride				D₃ Receptor, Ki: 1.4
Brexpiprazole hydrochloride			D_2L Receptor, Ki: 0.3 nM
MOR agonist-2				D₃ Receptor
Acetophenazine			D₂ Receptor
PAOPA			D₂ Receptor
Perphenazine dihydrochloride			D₂ Receptor, Ki: 0.56 nM	D₃ Receptor, Ki: 0.43 nM	D₄ Receptor, Ki: 28.5 nM
Lisuride			D₂ Receptor
Promazine			D₂ Receptor
Asenapine citrate		D₁ Receptor, pKi: 8.9	D₂ Receptor, pKi: 8.9	D₃ Receptor, pKi: 9.4	D₄ Receptor, pKi: 9.0
Cabergoline-d₆			D₂ Receptor	D₃ Receptor
BGC20-761			Human D₂ Receptor, Ki: 140 nM
Alizapride-¹³C,d₃ hydrochloride				D₃ Receptor
Risperidone-d₆			D₂ Receptor, Ki: 5.9 nM
SKF 38393 hydrobromide		D₁ Receptor, IC₅₀: 110 nM
D4R antagonis-2					D₄ Receptor, IC₅₀: 6.87 μM
A68930		D₁ Receptor
Dopamine D3 receptor ligand-3			D₂ Receptor, Ki: 353 nM	D₃ Receptor, Ki: 3.6 nM
Nemonapride			D₂ Receptor, Ki: 0.06 nM
SCH-23390 maleate		D₁ Receptor, Ki: 0.2 nM				D₅ Receptor, Ki: 0.3 nM
Itopride-d₆ hydrochloride			D₂ Receptor
Piribedil dihydrochloride			D₂ Receptor	D₃ Receptor
Cinitapride monotartrate			D₂ Receptor
Benztropine-¹³C,d₃ mesylate			D₂ Receptor	D₃ Receptor
PD 168568 dihydrochloride			D₂ Receptor, Ki: 1842 nM	D₃ Receptor, Ki: 2682 nM	D₄ Receptor, Ki: 8.8 nM
Ziprasidone mesylate			Rat D₂ Receptor, Ki: 4.8 nM
Dopamine D3 receptor ligand-4			D₂ Receptor, Ki: 7.43 nM	D₃ Receptor, Ki: 0.5 nM
L-745870 trihydrochloride			D₂ Receptor, Ki: 960 nM	D₃ Receptor, Ki: 2300 nM	Human D₄ Receptor, Ki: 4.3 nM
(Rac)-Rotigotine-d₇ hydrochloride		D₁ Receptor		D₃ Receptor	D₄ Receptor
Levosulpiride-d₃				D₃ Receptor			99.79%
Asenapine-¹³C,d₃ hydrochloride				D₃ Receptor	D₄ Receptor
Brexpiprazole S-oxide			D₂ Receptor, Ki: 0.3 nM
(S)-Remoxipride		D₁ Receptor, IC₅₀: ＞100 μM	D₂ Receptor, IC₅₀: 1.57 μM
PD 168568			D₂ Receptor, Ki: 1842 nM	D₃ Receptor, Ki: 2682 nM	D₄ Receptor, Ki: 8.8 nM
Blonanserin-d₅			D₂ Receptor
Aripiprazole monohydrate			D₂ Receptor	D₃ Receptor	D₄ Receptor
DETQ		Human D₁ Receptor, EC₅₀: 5.8 nM
Itopride			D₂ Receptor
Pramipexole-d₇ dihydrochloride			D₂ Receptor	D₃ Receptor	D₄ Receptor
FGH31					Dopamine D4 receptor, Ki: 1.6 nM
Ziprasidone mesylate trihydrate			Rat D₂ Receptor, Ki: 4.8 nM
Asimilobine	Dopamine Receptor
Piribedil hydrochloride			D₂ Receptor	D₃ Receptor
NEO 376	Dopamine Receptor						99.23%
Loxapine hydrochloride		Human D₁ Receptor	Human D₂ Receptor		Human D₄ Receptor
PNU-177864 hydrochloride				D₃ Receptor
Bromperidol hydrochloride			D₂ Receptor				99.96%
Bifeprunox			D₂ Receptor, pKi: 8.83 (striatum)
Antipsychotic agent-2			D₂ Receptor, Kb: 45.7 nM
BP 897			D₂ Receptor	D₃ Receptor
UNC9994			D₂ Receptor, Ki: 79 nM	D₃ Receptor, Ki: 17 nM	D₄ Receptor, Ki: 138 nM
Cyclo(glycyl-L-leucyl)	Dopamine Receptor
Dopamine D3 receptor ligand-2			D₂ Receptor, Ki: 1228 nM	D₃ Receptor, Ki: 11.4 nM
SKF83822 hydrobromide		D₁ Receptor
Haloperidol-d₄-1			D₂ Receptor				≥98.0%
Pramipexole-d₅ dihydrochloride			D₂ Receptor	D₃ Receptor	D₄ Receptor
Flupentixol		D₁ Receptor	D₂ Receptor
Tiapride			D₂ Receptor, IC₅₀: 110-320 nM	D₃ Receptor, IC₅₀: 180 nM
FAUC 213			hD₂ Receptor, Ki: 3.4 μM	hD₃ Receptor, Ki: 5.3 μM	hD_4.4 Receptor, Ki: 2.2 nM		99.86%
PNU-96415E					D₄ Receptor
Ecopipam		D₁ Receptor, Ki: 1.2 nM	D₂ Receptor, Ki: 980 nM		D₄ Receptor, Ki: 5520 nM	D₅ Receptor, Ki: 2.0 nM
Raclopride tartrate		D₁ Receptor, Ki: 18000 nM	D₂ Receptor, Ki: 1.8 nM	D₃ Receptor, Ki: 3.5 nM	D₄ Receptor, Ki: 2400 nM
Sonepiprazole			rD₂ Receptor, Ki: 5147 nM		rD₄ Receptor, Ki: 3.6 nM		99.84%
PG01037 dihydrochloride				D₃ Receptor, Ki: 0.7 nM
Haloperidol-d₄ N-Oxide			D₂ Receptor
Risperidone mesylate			D₂ Receptor, Ki: 5.9 nM
Iloperidone hydrochloride		Rat D₁ Receptor, Ki: 546 nM Human D₁ Receptor, Ki: 216 nM	Rat D₂ Receptor, Ki: 54 nM	Human D₃ Receptor, Ki: 7.1 nM	Human D₄ Receptor, Ki: 25 nM	Human D₅ Receptor, Ki: 319 nM
Sumanirole			D₂ Receptor
Pardoprunox			D₂ Receptor, pEC₅₀: 8	D₃ Receptor, pEC₅₀: 9.2
Pimozide-d₅ N-Oxide		D₁ Receptor		D₃ Receptor
Clocapramine			D₂ Receptor
Abaperidone			D₂ Receptor, IC₅₀: 17 nM
NRA-0160				D₃ Receptor, Ki: 39 nM	D₄ Receptor, Ki: 0.48 nM
Dexpramipexole-d₃ dihydrochloride				D₃ Receptor
Raclopride-d₅ hydrochloride				D₃ Receptor			99.82%
Clocapramine dihydrochloride hydrate			D₂ Receptor
(-)-GSK598809				D₃ Receptor
BP 897 hydrochloride			D₂ Receptor	D₃ Receptor			99.84%

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