1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Aam-KTX

Aam-KTX 是一种 Kv 通道抑制剂,其对 Kv1.3 和 Kv1.1 的 IC50 值分别为 1.1 nM 和 >750 nM。Aam-KTX 是一种可从蝎子 Mesobuthus eupeus 毒液当中获取的毒性肽。Aam-KTX 有用于研究自身免疫性疾病的潜力。

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Custom Peptide Synthesis

Aam-KTX Chemical Structure

Aam-KTX Chemical Structure

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aam-KTX is a Kv channel inhibitor with IC50 values of 1.1 nM and >750 nM for Kv1.3 and Kv1.1, respectively. Aam-KTX is a toxic peptide obtained from the venom of the scorpion Mesobuthus eupeus. Aam-KTX has potential in autoimmune diseases research[1].

IC50 & Target

IC50: 1.1 nM (Kv1.3), >750 nM (Kv1.1)[1].

分子量

4184.96

Formula

C174H288N58O48S7

Sequence

Gly-Val-Glu-Ile-Asn-Val-Lys-Cys-Thr-Gly-Ser-His-Gln-Cys-Ile-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Ile-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys-NH2 (Disulfide bridge:Cys8-Cys28;Cys14-Cys33;Cys18-Cys35)

Sequence Shortening

GVEINVKCTGSHQCIKPCKDAGMRFGKCINRKCHCTPK-NH2 (Disulfide bridge:Cys8-Cys28;Cys14-Cys33;Cys18-Cys35)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Aam-KTX
目录号:
HY-P5853
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