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  5. Ajugasterone C

Ajugasterone C  (Synonyms: 筋骨草甾酮C)

目录号: HY-N2196
产品使用指南 技术支持

Ajugasterone C 是一种从 Leuzea carthamoides 中分离出来的蜕化类固醇。在100 mg/kg 剂量下,Ajugasterone C 对在Carrageenan-诱导的 Sprague Dawley 大鼠足水肿的发生具有显著的抑制作用。

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Ajugasterone C

Ajugasterone C Chemical Structure

CAS No. : 23044-80-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Huh-7 CC50
> 700 μM
Compound: 3
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
[PMID: 26988299]
Huh-7 EC50
10.05 μM
Compound: 3
Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
12.15 μM
Compound: 3
Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
15.7 μM
Compound: 3
Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
9.48 μM
Compound: 3
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
分子量

480.63

Formula

C27H44O7

CAS 号
中文名称

筋骨草甾酮C

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ajugasterone C
目录号:
HY-N2196
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