2. GPCR/G Protein
  3. Apelin Receptor (APJ)
  4. (Ala13)-Apelin-13

(Ala13)-Apelin-13 是一种有效的 APJ 受体拮抗剂。(Ala13)-Apelin-13 通过迷走神经胆碱能通路抑制胃动力。

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Custom Peptide Synthesis

(Ala13)-Apelin-13 Chemical Structure

(Ala13)-Apelin-13 Chemical Structure

CAS No. : 568565-11-7

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(Ala13)-Apelin-13 的其他形式现货产品:

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Other Forms of (Ala13)-Apelin-13:

(Ala13)-Apelin-13 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway[1].

体内研究
(In Vivo)

(Ala13)-Apelin-13 (1-300 pmol/60 nl；显微注射到 DVC 中) 以剂量依赖性方式降低大鼠的胃张力和胃动力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 250-300 g, Sprague-Dawley rats[1]
Dosage: 1-300 pmol/60 nl
Administration: Microinjected into the DVC (dorsal vagal complex (DVC)
Result: Decreased gastric tone and motility in a dose-dependent manner with D50 ≈ 27 pmol for both antrum and corpus.
分子量

1474.73

Formula

C63H107N23O16S
CAS 号
Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala
Sequence Shortening

QRPRLSHKGPMPA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(Ala13)-Apelin-13 相关分类

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Keywords:

(Ala13)-Apelin-13568565-11-7Apelin Receptor (APJ)gastric tonemotilitycholinergic pathwayvagusdorsal vagal complexInhibitorinhibitorinhibit

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