1. Cell Cycle/DNA Damage Anti-infection
  2. Antibiotic DNA/RNA Synthesis Bacterial
  3. Albomycin

Albomycin 是一种氨酰 tRNA 合成酶抑制剂,具有特洛伊木马效应。Albomycin 通过高铁色素 (ferrichrome) 特异性的转运体系统,被铁螯合元件送进细菌体内。Albomycin 对广泛的革兰氏阳性和阴性细菌具有对抗作用。Albomycin 也是生产者的有效的铁清除剂。

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Albomycin Chemical Structure

Albomycin Chemical Structure

CAS No. : 1414-39-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer[1].

体外研究
(In Vitro)

Albomycin 也与 FhuA 结合,与高铁色素竞争结合位点。FhuA 是埋在大肠杆菌外膜的 β 桶。 或者,Albomycin 结合 FhuD,FhuD 是细胞膜 ABC 转运蛋白 FhuB/FhuC 的质周亚基[1]
Albomycin 对肺炎链球菌的生长有明显的抑制作用,最低抑制浓度为 4-62 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Albomycin
目录号:
HY-142072
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