1. Anti-infection
  2. Bacterial Antibiotic
  3. Amphomycin

Amphomycin 是一种脂肽抗生素,能抑制肽聚糖合成并阻断细胞壁发育。Amphomycin 对耐甲氧西林金黄色葡萄球菌 (MRSA)、耐万古霉素肠球菌 (VRE)、耐青霉素-庆大霉素-红霉素肺炎链球菌和耐利奈唑胺-奎奴普汀-达福普汀肠球菌表现出有效的抗菌活性。

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Custom Peptide Synthesis

Amphomycin Chemical Structure

Amphomycin Chemical Structure

CAS No. : 1402-82-0

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规格 价格 是否有货 数量
1 mg ¥6653
3 - 4 周
5 mg   询价  
10 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci[1][2][3].

IC50 & Target

Lipopeptide

 

体外研究
(In Vitro)

Amphomycin (40 μ g/mL; 60 min) leads S. aureus to exhibit cell wall thinning and Park’s nucleotide accumulation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: S. aureus whole cells
Concentration: 40 μ g/mL
Incubation Time: 60 min
Result: Resulted in the thinning of cell wall and the accumulation of Park’s nucleotide.
体内研究
(In Vivo)

Amphomycin (50 mg/kg; p.o.; single) shows low oral availability and (5-10mg/kg; i.v.; single) exhibits a long half-life (5.2-8.0 h in mice and 4.6-7.1 h in rats)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Amphomycin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Amphomycin
目录号:
HY-P3078
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