2. Epigenetics PI3K/Akt/mTOR
  3. AMPK
  4. AMPK activator 8

AMPK activator 8 (compound 2) 是一种 AMP 激活的蛋白激酶 (AMPK)激活剂，对 rAMPK α1β1γ1、rAMPK α2β1γ1、rAMPK α1β2γ1、rAMPK α2β2γ1、rAMPK α2β2γ3 的 EC50 分别为 11、27、4、2 和 4 nM。AMPK activator 8 可用于 2 型糖尿病的研究。

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AMPK activator 8 Chemical Structure

AMPK activator 8 Chemical Structure

CAS No. : 1852451-96-7

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AMPK activator 8 相关抗体

Top Publications Citing Use of Products

查看 AMPK 亚型特异性产品:

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1].

IC50 & Target

AMPK α1β1γ1

11 nM (EC50)

AMPK α2β1γ1

27 nM (EC50)

AMPK α1β2γ1

4 nM (EC50)

AMPK α2β2γ1

2 nM (EC50)

体外研究
(In Vitro)

AMPK activator 8 (compound 2) acts on rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ and rAMPK α2β2γ3 with the EC50 value of 11 nM, 27 nM, 4 nM, 2 nM and 4 nM, respectively[1].
AMPK activator 8 (compound 2) affects cell viability[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AMPK activator 8 相关抗体:

Cell Viability Assay[1]

Cell Line: HepG2, C2C12 myoblasts
Concentration: 0.01-1000 μM
Incubation Time: 1 hour
Result: Resulted in HepG2 and C2C12 myoblasts with the EC50 value of 255 nM and 230 nM, respectively.
分子量

480.90

Formula

C25H21ClN2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AMPK activator 8 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMPK activator 81852451-96-7AMPK activator8AMPK activator-8AMPKAMP-activated protein kinaseAMPK?activatortype 2 diabetesInhibitorinhibitorinhibit

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