2. Anti-infection
  3. Parasite
  4. Anti-infective agent 9

Anti-infective agent 9 (compound 1) 是恶性疟原虫抑制剂 (IC50=600 nM)，可下调疟原虫中的丙酮酸水平和 TCA 循环。Anti-infective agent 9 具有良好的代谢稳定性和对人类肝细胞的低毒性。研究发现，Anti-infective agent 9 抑制恶性疟原虫的潜在靶点并不是 1-脱氧-d-木酮糖-5-磷酸合酶 (DXPS)。

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Anti-infective agent 9 Chemical Structure

Anti-infective agent 9 Chemical Structure

CAS No. : 758689-17-7

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Anti-infective agent 9 相关抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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生物活性

Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC50=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS)[1].

IC50 & Target

IC50: 600 nM (P. falciparum)[1]
分子量

356.39

Formula

C14H11F3N4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Anti-infective agent 9 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-infective agent 9758689-17-7ParasiteDXPSMEP pathwayPlasmodium falciparumPolypharmacologymalariaInhibitorinhibitorinhibit

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Anti-infective agent 9
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