CD11b 抗体 (YA3423)

CD11b Antibody (YA3423) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD11b.

CD11b：启用补体组件 C3b 绑定活动；硫酸乙酰肝素蛋白多糖结合活性；和肝素结合活性。有助于货物受体活动。参与几个过程，包括中枢神经系统发育；内吞作用；和神经元死亡的正调节。作用于几个过程的上游或内部，包括激活的 T 细胞增殖；白细胞迁移；和小胶质细胞的发育。位于质膜和细胞核的外侧。是膜的组成部分。整合素 alphaM-beta2 复合体的一部分。以多种结构表达，包括中枢神经系统；心;淋巴管;胸腺;和卵黄囊。该基因的人类直系同源物与狼疮性肾炎有关。与人类 ITGAM（整合素亚基 alpha M）同源。[由基因组资源联盟提供，2022 年 4 月]

P11215

Predicted band size: 127 kDa;Observed band size: 170 kDa

affinity purified

Non-conjugated

Unmodified

AB_3676578

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human

WB: 1:500-1:1000; IHC: 1:50-1:100; IF: 1:50-1:200; IP: 1:50; FC: 1:50-1:100;

• 
  Western blot analysis of extracts from TF-1(lane 2(20ug) , THP-1(lane 3(20ug) and U937(lane 4(20ug) using CD11b Antibody (HY-P83690) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

WB, IHC-P, ICC/IF, IP, FC

液体

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human CD11b