OGG1 抗体 (YA3356)

OGG1 Antibody (YA3356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to OGG1.

The related gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of The enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of The related gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for The related gene have been described, but the full-length nature for every variant has not been determined.

O15527

Predicted band size: 39 kDa; Observed band size: 39 kDa

Affinity Chromatography

Non-conjugated

Unmodified

AB_3105718

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1:500-1:1000

• 
  Western blot analysis of extracts from HepG2 (lane 2(20μg) and HepG2 (lane 3(40μg) using OGG1 (HY-P83611) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

WB

液体

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human OGG1