1. Anti-infection
  2. SARS-CoV Bacterial
  3. Antimicrobial agent-10

Antimicrobial agent-10 是一种 SARS-CoV-2 抑制剂,具有优秀的抗菌活性。

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Antimicrobial agent-10 Chemical Structure

Antimicrobial agent-10 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antimicrobial agent-10 is a SARS-CoV-2 inhibitor with outstanding antibacterial activity[1].

IC50 & Target

Bacteria, SARS-CoV-2[1]

体外研究
(In Vitro)

Antimicrobial agent-10 (compound 4) shows inhibitory activity on coronavirus (SARS-CoV-2, HCoV-229E) replication and spike-mediated pseudovirus entry in Vero E6 cells, Calu-3 cells, A549-AT cells, with EC50 values of 13-22 μM[1].
Antimicrobial agent-10 inhibits cathepsin L, 3CLPro enzyme activity and the ACE2-spike interaction, with EC50 values of 66 μM, 7.6 μM, 9 μM respectively[1].
Antimicrobial agent-10 (0-10 μg/mL approximately) shows activity against diverse species of Gram-positive bacteria including drug-resistant strains[1].
Antimicrobial agent-10 (0-100 μM, 2 h) inhibits SARS-CoV-2 pseudovirus entry in Vero and A549-AT cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: S. aureus, E. faecalis, E. faecium, S. epidermidis, S. haemolyticus
Concentration: 0-10 μg/mL approximately
Incubation Time:
Result: Inhibited bacteria activities with MIC values of 0.25-6.8 μg/mL.
分子量

1844.29

Formula

C78H65Cl2F13N10O24

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antimicrobial agent-10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antimicrobial agent-10
目录号:
HY-151497
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