Argipressin diacetate  (Synonyms: Arg8-vasopressin diacetate; AVP diacetate; ADH)

Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes^[1].

Argipressin (diacetate) (AVP (diacetate)) induces proliferation and prevented cytokine-induced apoptosis in rodent and human beta-cells^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Argipressin (diacetate) (AVP (diacetate)) (25 nmol/kg bw; intraperitoneal injection; once) significantly reduces overall AUC glucose values，but not increases insulin levels in mice^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1204.34

C₅₀H₇₃N₁₅O₁₆S₂

75499-44-4

CYFQNCPRG-NH2 (Disulfide bridge: Cys1-Cys6)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Shruti Mohan, et al. Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. Biochimie  [Content Brief]