1. Anti-infection
  2. HIV
  3. Azt-pmap

Azt-pmap 

目录号: HY-120832
产品使用指南

Azt-pmap,是核苷类似物,一种 AZT 的磷酸芳基衍生物。Azt-pmap 显示抗 HIV 活性。AZT 是一种用于 HIV 感染的核苷逆转录酶抑制剂 (NRTI)。

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Azt-pmap Chemical Structure

Azt-pmap Chemical Structure

CAS No. : 142629-81-0

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Description

Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity[1]. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2].

IC50 & Target

HIV-1

 

In Vitro

Azt-pmap shows anti-HIV-1 activities in infected C8166 and JM cells with EC50s of 0.08 and0.32 μM, respectively. Azt-pmap displays toxicities in infected C8166 and JM cells with TC50s of 500 μM, respectively. Azt-pmap inhibits virus replication[1].

Molecular Weight

508.42

Formula

C₂₀H₂₅N₆O₈P

CAS No.

142629-81-0

SMILES

O=C(NC1=O)N(C=C1C)[C@@H]2O[C@H](COP(OC3=CC=CC=C3)(N[C@@H](C)C(OC)=O)=O)[C@@H](N=[N+]=[N-])C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Azt-pmapHIVHuman immunodeficiency virusderivativeHIV1virusreplicationtoxicitiesinfectionnucleosideanalogueInhibitorinhibitorinhibit

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产品名称:
Azt-pmap
目录号:
HY-120832
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