1. Anti-infection
    Cell Cycle/DNA Damage
  2. HCV
    DNA/RNA Synthesis
  3. Balapiravir hydrochloride

Balapiravir hydrochloride (Synonyms: Ro 4588161 hydrochloride; R1626 hydrochloride)

目录号: HY-10443A
产品使用指南

Balapiravir (Ro 4588161 hydrochloride; R1626 hydrochloride) 是具有口服活性的 R1479 (4'-Azidocytidine) 的前药,R1479 是一种 HCV RNA 依赖性 RNA 聚合酶 (RdRp) 的核苷类似物抑制剂。Balapiravir hydrochloride 具有抗 HCV 活性。

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Balapiravir hydrochloride Chemical Structure

Balapiravir hydrochloride Chemical Structure

CAS No. : 690270-65-6

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Balapiravir hydrochloride 的其他形式现货产品:

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生物活性

Balapiravir hydrochloride (Ro 4588161 hydrochloride; R1626 hydrochloride) is an orally active prodrug of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine). Balapiravir hydrochloride has anti-HCV activity[1][2][3].

体外研究
(In Vitro)

After oral dosing of the CD-1 mice with 28.1 mg/kg of balapiravir (Ro 4588161 hydrochloride; R1626 hydrochloride), R1479 reaches a Cmax and a minimum concentration in plasma (Cmin) of 24.38 μM and 6.34 μM, respectively, at 2 h and 24 h postdosing[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

530.96

Formula

C21H31ClN6O8

CAS 号
中文名称

4'-C-迭氮基胞嘧啶核苷2',3',5'-三异丁酸酯盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
Balapiravir hydrochloride
目录号:
HY-10443A
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