1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. BChE-IN-32

BChE-IN-32 (compound 5d) 是一种有效的选择性 hBChE 抑制剂,IC50 值为 0.109 µM。BChE-IN-32 显示细胞毒性。BChE-IN-32 具有研究阿尔茨海默病的潜力。

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BChE-IN-32 Chemical Structure

BChE-IN-32 Chemical Structure

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查看 Cholinesterase (ChE) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ChE-IN-32 (compound 5d) is a potent and selective hBChE inhibitor with an IC50 value of 0.109 µM. BChE-IN-32 shows cytotoxicity. BChE-IN-32 has the potential for the research of Alzheimer's disease[1].

IC50 & Target[1]

hBCHE

0.109 μM (IC50)

体外研究
(In Vitro)

BChE-IN-32 (compound 5d) (0-200 µM) 对 SH-SY5Y 和 HepG2 细胞具有细胞毒性,IC50 值分别为 110.0 和 42 µM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: SH-SY5Y, HepG2 cells
Concentration: 0-200 µM
Incubation Time:
Result: Showed cytotoxicity with IC50s of 110.0, 42 µM for SH-SY5Y, HepG2 cells, respectively.
分子量

407.59

Formula

C26H37N3O

Unlabeled CAS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

BChE-IN-32 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BChE-IN-32
目录号:
HY-161453
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