2. Anti-infection
  3. HCV
  4. BMS-929075

BMS-929075 是一种有效的口服活性 HCV NS5B 复制酶 (HCV NS5B replicase) 手掌位点变构抑制剂。BMS-929075 显示出高口服生物利用度。BMS-929075 显示出细胞毒性。

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BMS-929075 Chemical Structure

BMS-929075 Chemical Structure

CAS No. : 1217338-97-0

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规格 价格 是否有货 数量
1 mg ￥2261
1 周
5 mg   询价  
10 mg   询价  

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Customer Review

BMS-929075 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS-929075 is a potent and orally active HCV NS5B replicase palm site allosteric inhibitor. BMS-929075 shows high oral bioavailability. BMS-929075 shows cytotoxicity[1].

体外研究
(In Vitro)

BMS-929075 (0-60 µM) 显示细胞毒性，对于 Huh-7、HepG2、原代人肝细胞的CC50 值分别为 60、>12.5、>50 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BMS-929075 相关抗体:
体内研究
(In Vivo)

BMS-929075 (compound 37) (静脉注射 2 mg/kg；口服 6 mg/kg) 显示出良好的药代动力学参数，大鼠口服生物利用度为 48%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

538.54

Formula

C31H24F2N4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BMS-929075 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-9290751217338-97-0BMS929075BMS 929075HCVHepatitis C virusorally activecytotoxicityHuh-7HepG2 cellsInhibitorinhibitorinhibit

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目录号：
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