2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Brevetoxin B

Brevetoxin B  (Synonyms: Brevetoxin-2; PbTx-2)

目录号: HY-12546
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摩尔计算器

Brevetoxin B (Brevetoxin-2) 是一种由 Karenia 种或其他甲藻产生的多聚酮类神经毒素 (neurotoxin)。Brevetoxin B 结合到神经肌肉连接处神经元< B >电压门控钠通道 (voltage-gated sodium channels) 的 α 亚基的 5 位 (IC50=15 nM)，导致该通道在电位比正常电位更负时不可逆地打开，重复放电动作电位。

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Brevetoxin B Chemical Structure

Brevetoxin B Chemical Structure

CAS No. : 79580-28-2

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规格 价格 是否有货 数量
100 μg ￥5810
3 - 4 周

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Brevetoxin B 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Brevetoxin B binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50=15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively.

分子量

895.08

Formula

C50H70O14
CAS 号
结构分类
初始来源

Austrovenus stutchburyi
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Brevetoxin B 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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Keywords:

Brevetoxin B79580-28-2Brevetoxin-2 PbTx-2Brevetoxin2Brevetoxin 2PbTx2PbTx 2PbTx-2Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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