2. Epigenetics
  3. Epigenetic Reader Domain
  4. BRM/BRG1 ATP Inhibitor-3

BRM/BRG1 ATP Inhibitor-3 是一种 BRG1/BRM 抑制剂。BRM/BRG1 ATP Inhibitor-3 抑制 BRM 和 BRG1，IC50 值分别为 10.4 nM 和 19.3 nM。BRM/BRG1 ATP Inhibitor-3 可用于癌症和 BAF 复合物相关疾病的研究。

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BRM/BRG1 ATP Inhibitor-3 Chemical Structure

BRM/BRG1 ATP Inhibitor-3 Chemical Structure

CAS No. : 2368901-31-7

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BRM/BRG1 ATP Inhibitor-3 相关抗体

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  • 生物活性

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生物活性

BRM/BRG1 ATP Inhibitor-3 is a BRG1/BRM inhibitor. BRM/BRG1 ATP Inhibitor-3 inhibits BRM and BRG1 with IC50 values of 10.4 nM and 19.3 nM, respectively. BRM/BRG1 ATP Inhibitor-3 can be used for the research of cancers and BAF complex-related disorders[1].

IC50 & Target

IC50: 10.4 nM (BRM); 19.3 nM (BRG1)[1].
体外研究
(In Vitro)

BRM/BRG1 ATP Inhibitor-3 has inhibitory activity for BRM and BRG1 with IC50 values of 10.4 nM and 19.3 nM, respectively[1].
BRM/BRG1 ATP Inhibitor-3 (0.01-10 μM) has inhibition for cell proliferation in several cancer cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BRM/BRG1 ATP Inhibitor-3 相关抗体:

Cell Proliferation Assay[1]

Cell Line: Uveal melanoma cell lines (92-1 , MP41 , MP38, MP46), prostate cancer cell lines (LNCAP), lung cancer cell lines (NCI-H1299), and immortalized embryonic kidney lines (HEK293T)
Concentration: 0-10 μM
Incubation Time: 3 days
Result: Inhibited cell proliferation of uveal melanoma cell line 92-1 and MP41.
分子量

503.64

Formula

C26H25N5O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BRM/BRG1 ATP Inhibitor-3 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BRM/BRG1 ATP Inhibitor-32368901-31-7Epigenetic Reader DomainBRG1/BRMinhibitorycancersBAF complex-related disordersInhibitorinhibitorinhibit

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