1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. c-Fms-IN-9

c-Fms-IN-9 

目录号: HY-128680
产品使用指南

c-Fms-IN-9 是一种 c-FMS 抑制剂,详细信息请参考专利文献 WO2014145023A1 中的化合物 Example 7。c-Fms-IN-9 抑制非磷酸化的 c-FMS 激酶 (uFMS) 和 uKITIC50 分别为 <0.01 μM 和 0.1-1 μM。

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c-Fms-IN-9 Chemical Structure

c-Fms-IN-9 Chemical Structure

CAS No. : 1628574-50-4

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Description

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

IC50 & Target

c-FMS[1]

In Vitro

c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].

Molecular Weight

405.45

Formula

C₂₁H₂₃N₇O₂

CAS No.

1628574-50-4

SMILES

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
c-Fms-IN-9
目录号:
HY-128680
需求量:

c-Fms-IN-9

Cat. No.: HY-128680