2. 天然产物
  3. 植物 酮、醛、酸
  4. 十字花科
  5. 豆瓣菜
  6. Caffeoylmalic acid

Caffeoylmalic acid 是一种具有口服活性的羟基肉桂酰苹果酸酯，被发现存在于荨麻 (Urtica dioica) 中。Caffeoylmalic acid 具有抗糖尿病、抗炎和抗氧化作用。Caffeoylmalic acid 对癌细胞表现出细胞毒性。Caffeoylmalic acid 可用于癌症、炎症和代谢疾病的研究，如结肠癌和糖尿病。

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Caffeoylmalic acid

Caffeoylmalic acid Chemical Structure

CAS No. : 39015-77-5

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Caffeoylmalic acid 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Caffeoylmalic acid is an orally active hydroxycinnamoyl-malate ester found in stinging nettle (Urtica dioica). Caffeoylmalic acid exhibits anti-diabetic, anti-inflammation and anti-oxidant effects. Caffeoylmalic acid shows cytotoxicity to cancer cells. Caffeoylmalic acid can be used for the researches of cancer, inflammation and metabolic disease, such as colon cancer and diabetes[1][2][3].

体外研究
(In Vitro)

Caffeoylmalic acid (5-80 μM) 会增加酵母细胞对葡萄糖的吸收[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Caffeoylmalic acid 相关抗体:
体内研究
(In Vivo)

Caffeoylmalic acid (0.5 mg/kg，口服，每日一次，连续 21 天) 可降低四氧嘧啶 (alloxan) 诱导的糖尿病小鼠模型的血糖水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Alloxan-induced diabetic mice models[1]
Dosage: 0.5 mg/kg
Administration: Orally administration, daily for 21 days
Result: Reduced blood glucose level.
Increased body weight.
Induced the production of insulin.
Decreased total cholesterol, triglycerides and LDL as well as increased HDL.
Reduced the levels of SGOT, ALP and SGPT.
Increased RBC count and decreased WBC count.
分子量

296.23

Formula

C13H12O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Caffeoylmalic acid 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caffeoylmalic acid39015-77-5OthersStinging nettleUrtica dioicaCancerDiabetesInhibitorinhibitorinhibit

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