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  2. Reactive Oxygen Species
  3. Catalase

Catalase 

目录号: HY-135849
产品使用指南

Catalase 是重要的抗氧化酶,在清除 ROS。在维持氧化还原状态的平衡方面发挥着重要作用。Catalase 与肿瘤的发生,发展关系密切。有潜力用于肿瘤的预防研究。

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Catalase Chemical Structure

Catalase Chemical Structure

CAS No. : 9001-05-2

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Description

Catalase is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors[1]. Free oxygen radical scavenger.

In Vitro

Catalase, the enzyme that metabolizes H2O2 but also reacts with a multitude of other substrates. The active site of catalase contains an iron atom. Human catalase contains four identical subunits, each subunit containing four distinct domains and one prosthetic heme group. The four domains include: (1) a N-terminal arm which contains a distal histidine, an essential amino acid for the catalase reaction; (2) a β-barrel domain that contains eight β-barrels arranged in an antiparallel fashion with six α-helical insertions, conferring the hydrophobic core of the protein necessary for the tri-dimensional structure of the enzyme; (3) a connection domain which contains the tyrosine residue that binds the heme group; and finally (4) an α-helical domains, which is important for NADPH binding[1].

CAS No.

9001-05-2

SMILES

[Catalase]

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References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CatalaseReactive Oxygen SpeciesbreastcancerprostatelungAntioxidantEnzymeNADPHmetabolismH2O2reactiveoxygenspeciesROStumorInhibitorinhibitorinhibit

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产品名称:
Catalase
目录号:
HY-135849
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