2. GPCR/G Protein Neuronal Signaling Cell Cycle/DNA Damage Epigenetics
  3. Melanocortin Receptor Sirtuin
  4. Palmitoyl tetrapeptide-20 TFA

Palmitoyl tetrapeptide-20 TFA  (Synonyms: PTP20 TFA)

目录号: HY-P5247A
产品使用指南 技术支持

Palmitoyl tetrapeptide-20 (PTP20) TFA 是一种 α-MSH 激动剂仿生肽。Palmitoyl tetrapeptide-20 TFA 可通过激活 MC1-R (AC50: 0.16 nM) 通路、增强过氧化氢酶活性减少 H2O2 积累、并上调 SIRT1 活性等，促进头发色素沉着并延缓头发灰白进程。Palmitoyl tetrapeptide-20 TFA 可用于防脱发和改善头发灰白等方面的研究。

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Custom Peptide Synthesis

Palmitoyl tetrapeptide-20 TFA Chemical Structure

Palmitoyl tetrapeptide-20 TFA Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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Palmitoyl tetrapeptide-20 TFA 的其他形式现货产品:

Customer Review

Other Forms of Palmitoyl tetrapeptide-20 TFA:

Palmitoyl tetrapeptide-20 TFA 相关抗体

Top Publications Citing Use of Products

查看 Melanocortin Receptor 亚型特异性产品:

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MC1R MC3R MC2R MC4R MC5R

查看 Sirtuin 亚型特异性产品:

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Sirtuin SIRT1 SIRT2 SIRT3 SIRT6 SIRT5 SIRT7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 TFA promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 TFA can be used in research on preventing hair loss and improving hair graying[1].

IC50 & Target[1]

MC1R

 

SIRT1

 

体外研究
(In Vitro)

Palmitoyl tetrapeptide-20 (0.1-1 μM; 72 h) TFA 在人黑素细胞中促进黑色素生成[1]。
Palmitoyl tetrapeptide-20 (18 h) TFA 在毛囊真皮乳头细胞可降低细胞内 H2O2 水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Palmitoyl tetrapeptide-20 TFA 相关抗体:
分子量

739.00 (free base)

Formula

C38H70N6O8.xC2HF3O2
Sequence

{Pal}-Pro-Glu-Lys-Lys
Sequence Shortening

{Pal}-PEKK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Palmitoyl tetrapeptide-20 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palmitoyl tetrapeptide-20PTP20Palmitoyl tetrapeptide20Palmitoyl tetrapeptide 20PTP 20PTP-20Melanocortin ReceptorSirtuinMC Receptorα-MSHhair pigmentationhair greyingmelanocytesfollicle dermal papilla cellsInhibitorinhibitorinhibit

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目录号：
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