2. Immunology/Inflammation
  3. CD19
  4. CD19 CAR mRNA (Mouse)

CD19 CAR mRNA (Mouse) 表达小鼠 CD19 CAR 蛋白。CD19 CAR mRNA 可触发 CAR 的短暂表达，使 T 细胞无需永久性基因改造即可被靶向。CD19 CAR mRNA 靶向 CD19，CD19 是一种主要在 B 淋巴细胞上表达的跨膜糖蛋白，在 B 细胞活化中起重要作用。CD19 CAR mRNA 可用于淋巴瘤和白血病等癌症研究。

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CD19 CAR mRNA (Mouse)

CD19 CAR mRNA (Mouse) Chemical Structure

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100 μg ￥3600
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Other Forms of CD19 CAR mRNA (Mouse):

CD19 CAR mRNA (Mouse) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CD19 CAR mRNA (Mouse) expresses mouse CD19 CAR protein. CD19 CAR mRNA can trigger transitory expression of CAR, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA targets CD19 which is a transmembrane glycoprotein primarily expressed on B lymphocytes and is important in B cell activation. CD19 CAR mRNA can be studied in cancer research such as lymphoma and leukemia[1][2][3].

体外研究
(In Vitro)

CD19 CAR mRNA 与 DNA 电穿孔和慢病毒载体转导相比，可通过电穿孔产生更高水平的 CAR 阳性 NK 细胞[4]。
CD19 CAR mRNA可在数小时内检测到纯化或扩增的 NK 细胞的 CAR 表达和活性，并且在电穿孔后可持续数天[4]。
CD19 CAR mRNA (120 μM，24 小时) 与对照组相比，不会引起 NK-92 细胞系中的额外细胞死亡[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CD19 CAR mRNA (Mouse) 相关抗体:

Immunofluorescence[4]

Cell Line: NK-92 cell line
Concentration: 120 μM
Incubation Time: 24 h
Result: Resulted in 47.2% of the transfected cells expressing CAR protein on their surface.
Exhibited stable expression for up to 3 days and detectable up to 5 days.
性状

固体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 97.1%

COA (279 KB)

产品使用指南 (1538 KB)
参考文献

CD19 CAR mRNA (Mouse) 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CD19 CAR mRNA (Mouse)CD19CARlymphomaleukemiaInhibitorinhibitorinhibit

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