1. Epigenetics Cell Cycle/DNA Damage
  2. Epigenetic Reader Domain CRISPR/Cas9
  3. CEM114

CEM114 是一种有效的化学表观遗传修饰剂 (CEM),可通过 CRISPR-Cas9 系统募集内源性染色质机制。

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CEM114 Chemical Structure

CEM114 Chemical Structure

CAS No. : 2279062-54-1

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CEM114 is an effective chemical epigenetic modifier (CEM) that recruits endogenous chromatin machinery through CRISPR-Cas9 systems[1].

体外研究
(In Vitro)

CEM114 (200 nM; 48 hours) treatment significantly activates the Green Fluorescent Protein (GFP) signal, suggesting that excess FK506 is able to outcompete CEM114 from the FKBP binding site[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HEK 293T cells
Concentration: 200 nM
Incubation Time: 48 hours
Result: Significantly activated the GFP signal.
分子量

1612.98

Formula

C84H122FN9O19S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CEM114
目录号:
HY-136572
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