1. Protein Tyrosine Kinase/RTK
  2. c-Kit
  3. CHMFL-KIT-033

CHMFL-KIT-033 

目录号: HY-128589
产品使用指南

CHMFL-KIT-033 是一种有效、可选择性的 c-KIT T670I 突变型的抑制剂, IC50 值为 0.045 μM。用于胃肠道间质瘤 (GISTs) 的治疗。

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CHMFL-KIT-033 Chemical Structure

CHMFL-KIT-033 Chemical Structure

CAS No. : 2351801-41-5

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Description

CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1].

IC50 & Target

IC50: 0.045 μM (c-KIT T670I mutant)[1]

Molecular Weight

415.42

Formula

C₂₃H₁₈FN₅O₂

CAS No.

2351801-41-5

SMILES

O=C(CC(NC1=CC=CC(F)=C1)=O)NC2=CC(NN=C3/C=C/C4=CC=CC=N4)=C3C=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
CHMFL-KIT-033
目录号:
HY-128589
需求量:

CHMFL-KIT-033

Cat. No.: HY-128589