2. Metabolic Enzyme/Protease
  3. MetAP
  4. CKD-731

CKD-731 是 Fumagillin (HY-B0751) 的类似物。CKD-731 抑制小牛肺动脉内皮细胞、淋巴瘤 EL-4 细胞和小鼠白血病 P388D1 细胞的增殖。CKD-731 通过抑制 MetAP-2 活性并阻断血管生成发挥作用。CKD-731 可用于抗血管生成相关癌症的研究。

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CKD-731

CKD-731 Chemical Structure

CAS No. : 251111-15-6

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CKD-731 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CKD-731 is a Fumagillin (HY-B0751) analogue. CKD-731 inhibits the proliferation of calf pulmonary artery endothelial cells (CPAE), lymphoma EL-4 cells and murine leukemia P388D1 cells. CKD-731 exerts the effect of inhibiting MetAP-2 activity and blocking angiogenesis. CKD-731 can be used for the research of anti-angiogenesis-related cancer[1].

分子量

502.60

Formula

C28H38O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CKD-731 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CKD-731251111-15-6CKD731CKD 731MetAPMethionine Aminopeptidasecalf pulmonary artery endothelial cells (CPAE)lymphoma EL-4 cellsmurine leukemia P388D1 cellscancerInhibitorinhibitorinhibit

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目录号：
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