2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. COR170

COR170 (11u) 是一种选择性的 CB2 反向激动剂，是一种 4-喹诺酮-3-羧酸衍生物，对 CB2 的 Ki 值为 3.8 nM。COR170 可用于炎症和神经保护的研究。

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COR170 Chemical Structure

COR170 Chemical Structure

CAS No. : 1048039-15-1

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规格 价格 是否有货 数量
5 mg ￥3594
3 - 4 周
10 mg ￥5746
3 - 4 周
50 mg   询价  
100 mg   询价  

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Customer Review

COR170 相关抗体

Top Publications Citing Use of Products

查看 Cannabinoid Receptor 亚型特异性产品:

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CB1 CB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COR170 (11u) is a selective CB2 inverse-agonist which is a 4-quinolone-3-carboxylic acid derivative with a Ki value of 3.8 nM for CB2 receptor. COR170 can be used for the research of inflammation and neuroprotection[1][2][3].

体外研究
(In Vitro)

COR170 (11u) (0-1 μM) inhibits CB2 receptor in HEK cell membranes with a Ki value of 3.8 nM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

COR170 相关抗体:
体内研究
(In Vivo)

COR170 (11u) (1.5-6 mg/kg; i.p, once) reduces the late phase nociceptive behaviour induced by formalin[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice with formalin (1.25%, 30 μL) injections[3]
Dosage: 1.5, 3 and 6 mg/kg
Administration: Intraperitoneal injection; 1.5, 3 and 6 mg/kg for once
Result: Reduced the late phase nociceptive behaviour induced by formalin with a 6 mg/kg dose and 10 min before formalin and abolished the analgesic effect from GW405833 which is a CB2 receptor partial agonist.
分子量

468.63

Formula

C31H36N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

COR170 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COR1701048039-15-1COR 170COR-170Cannabinoid Receptorreperfusion4-Quinolone-3-carboxylic acid derivativesneuroprotectioncannabinoids systembrain slicesInhibitorinhibitorinhibit

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目录号：
HY-103331
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