2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. ATRA-hydroxyimino

ATRA-hydroxyimino  (Synonyms: CRABP-II ligand 1)

目录号: HY-111839
产品使用指南

摩尔计算器

ATRA-hydroxyimino (CRABP-II ligand 1) 是一种基于 Retinoic acid (ATRA) 的 moiety，可通过 linker 与 cIAP1 配体 (Bestatin) 结合从而形成 SNIPER 分子，可降解 IMR-32 细胞中 CRABP-II。

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ATRA-hydroxyimino Chemical Structure

ATRA-hydroxyimino Chemical Structure

CAS No. : 135325-47-2

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ATRA-hydroxyimino 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells[1].

IC50 & Target

CRABP-II, PROTAC[1].
分子量

329.43

Formula

C20H27NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATRA-hydroxyimino 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATRA-hydroxyimino135325-47-2CRABP-II ligand 1Ligands for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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目录号：
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