1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. CSF1R-IN-4

CSF1R-IN-4 是一种有效的 CSF1R 抑制剂。CSF-1R在巨噬细胞中表达,巨噬细胞的存活和分化依赖于CSF-1/CSF-1R信号通路。CSF1R-IN-4 影响 TAM 和胶质瘤细胞之间炎症因子的交换。CSF1R-IN-4 具有研究癌症疾病的潜力 (信息提取自专利 WO2021197276A1, 化合物 104)。

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CSF1R-IN-4 Chemical Structure

CSF1R-IN-4 Chemical Structure

CAS No. : 2716185-86-1

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CSF1R-IN-4 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104)[1].

分子量

428.44

Formula

C23H20N6O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

CSF1R-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CSF1R-IN-4
目录号:
HY-144040
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