1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 

目录号: HY-P3850
产品使用指南

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 是 Neurokinin B (Neurokinin Receptor) 的竞争性拮抗剂,pA2 为 5.5,对 Substance P 或 Neurokinin A 没有影响。

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Custom Peptide Synthesis

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B Chemical Structure

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B Chemical Structure

CAS No. : 109212-72-8

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规格 是否有货
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100 mg   询价  
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].

体内研究
(In Vivo)

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) significantly reduces Substance P- and Neurokinin B- but not acetylcholine- or Neurokinin A-induced salivation. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B lowers blood pressure in anesthetized rats by 35 to 40%[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1326.50

Formula

C67H87N15O14

CAS 号
Sequence Shortening

D-{D-Pro}-HDF-{D-Trp}-V-{D-Trp}-L-{Nle}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
目录号:
HY-P3850
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