1. Immunology/Inflammation
  2. CD3
  3. Dafsolimab

Dafsolimab  (Synonyms: SPV-T3a)

目录号: HY-P99837

Dafsolimab (SPV-T3a) 是一种 IgG2a 小鼠单克隆抗体 (抗 CD3)。Dafsolimab 可通过 CD3/T 细胞受体复合物的调节和激活诱导细胞死亡。Dafsolimab 可用于移植物抗宿主病 (GVHD) 的研究。

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Dafsolimab Chemical Structure

Dafsolimab Chemical Structure

CAS No. : 2367001-71-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dafsolimab (SPV-T3a) is an IgG2a murine monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD)[1].

体外研究
(In Vitro)

SPV-T3a-dgA (1.8 μg/mL) 在没有 PHA 激活的情况下,活细胞减少 2.0-2.7 倍。PHA激活48小时后,SPV-T3a-DGA 的最大杀伤力增加约 3 倍。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Dafsolimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dafsolimab
目录号:
HY-P99837
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