2. Others Membrane Transporter/Ion Channel Neuronal Signaling Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease NF-κB
  3. Reference Standards GABA Receptor Sigma Receptor iGluR PPAR NF-κB
  4. Dehydroepiandrosterone sulfate (Standard)

Dehydroepiandrosterone sulfate (Standard)  (Synonyms: DHEA sulfate (Standard); Prasterone sulfate (Standard))

目录号: HY-113416R 纯度: ≥98%
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Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) 是 Dehydroepiandrosterone sulfate (HY-113416) 的分析标准品。本产品用于研究及分析应用。Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) 是一种神经甾体和肾上腺的主要分泌产物。Dehydroepiandrosterone sulfate 同时具有 GABAA 受体的非竞争性拮抗剂和 σ1 受体的激动剂活性。Dehydroepiandrosterone sulfate 可部分透过血脑屏障，抑制 GABAA 受体介导的氯离子内流、通过 σ1 受体增强 NMDA 受体活性，发挥抗炎、抗糖皮质激素和抗抑郁的作用，并增加惊厥敏感性。Dehydroepiandrosterone sulfate 参与神经保护、神经突生长调控及儿茶酚胺分泌调节，可用于抑郁症、创伤后应激障碍 (PTSD)、阿尔茨海默病等研究。Dehydroepiandrosterone sulfate 也可能是心血管疾病死亡率的生物标志物，其浓度与死亡率呈独立且负相关的关系。

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Dehydroepiandrosterone sulfate (Standard) Chemical Structure

Dehydroepiandrosterone sulfate (Standard) Chemical Structure

CAS No. : 651-48-9

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规格 价格 是否有货 数量
1 mg ￥1375
In-stock
5 mg ￥2750
In-stock
10 mg ￥4120
In-stock
25 mg ￥7420
In-stock
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生物活性

Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality.

分子量

368.49

同用名

DHEA sulfate (Standard); Prasterone sulfate (Standard)

Formula

C19H28O5S
CAS 号
性状

固体

颜色

White to off-white

初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Dehydroepiandrosterone sulfate (Standard) 相关分类

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质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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Keywords:

Dehydroepiandrosterone sulfate (Standard)651-48-9DHEA sulfate (Standard)Prasterone sulfate (Standard)Reference StandardsGABA ReceptorSigma ReceptoriGluRPPARNF-κBGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorIonotropic glutamate receptorsPeroxisome proliferator-activated receptorsNuclear factor-κBNuclear factor-kappaBTBIDHEADHEASInhibitorinhibitorinhibit

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