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  2. Dentonin

Dentonin (Synonyms: AC-100)

目录号: HY-P2633
产品使用指南

Dentonin (AC-100) 是 MEPE 来源的短肽片段。Dentonin 通过促进骨祖细胞粘附而促进成骨作用,并且可以促进未成熟的贴壁细胞存活。Dentonin 对成熟成骨细胞无显著影响。Dentonin 可用于磷酸盐稳态和骨代谢的研究。

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Dentonin Chemical Structure

Dentonin Chemical Structure

CAS No. : 400090-20-2

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Description

Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism[1].

In Vitro

MEPE is a a member of the SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) family of secreted glycophosphoproteins.  MEPE  regulates bone mass and influence osteoblast activity.[1].
Dentonin (3-30 μg/ml; 2-24 hours) significantly increases the numbers of cell and shows enhanced promotion of cell adhesion. However, it has no significant differences in terms of numbers of cells adhered[2].
Dentonin (3-30 μg/ml; 2-24 hours) enhances osteoblast spreading, it exhibits significantly increased cell areas compared to all other treatment[2].

Molecular Weight

2538.59

Formula

C₁₀₇H₁₆₀N₃₀O₄₂

CAS No.

400090-20-2

Sequence Shortening

TDLQERGDNDISPFSGDGQPFKD

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

DentoninAC-100AC100AC 100OthersOsteogenesis Inducercell adhesionosteoblastfocal complex formationInhibitorinhibitorinhibit

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产品名称:
Dentonin
目录号:
HY-P2633
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