2. GPCR/G Protein
  3. GCGR
  4. [Des-His1,Glu9] Glucagon

[Des-His1,Glu9] Glucagon是一种有效的胰高血糖素受体系统多肽拮抗剂。[Des-His1,Glu9] Glucagon 增强胰岛细胞在葡萄糖刺激下释放胰岛素。[Des-His1,Glu9] Glucagon 可用于糖尿病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

[Des-His1,Glu9] Glucagon Chemical Structure

[Des-His1,Glu9] Glucagon Chemical Structure

CAS No. : 110121-11-4

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

[Des-His1,Glu9] Glucagon 相关抗体

注册 MCE会员 并 完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes[1].

IC50 & Target

Glucagon Receptor[1]
体外研究
(In Vitro)

[Des-His1,Glu9] Glucagon (1 pM-100 μM) does not activate membrane-bound adenylate cyclase up to a concentration of 2×10-4 molar in the cAMP assay on isolated rat liver membranes (from male Sprague Dawley rats)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

[Des-His1,Glu9] Glucagon 相关抗体:
体内研究
(In Vivo)

[Des-His1,Glu9] Glucagon (3.6-4.0 μg/kg for rabbits, 1 mg/kg for rats; i.v.; single dosage) suppresses hyperglycemic effects in rabbits and rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: New Zealand rabbits (2.8-3.8 kg; fasted for 18 hours)[1]
Dosage: 3.6-4.0 μg/kg
Administration: i.v.; single dosage
Result: Suppressed hyperglycemic response of glucagon.
Animal Model: Male Wistar rats weighing [350-400 mg; hyperglycemia induced by i.p. injection of 65 mg/kg Streptozotocin (HY-13753)][1]
Dosage: 1 mg/kg
Administration: Intravenously administration through the tail vein; single dosage
Result: Decreased blood glucose rapidly, and reduced hyperglycemic effect by 70% within 5 min.
分子量

3359.63

Formula

C148H220N40O48S
CAS 号
Sequence Shortening

SQGTFTSEYSKYLDSRRAQDFVQWLMNT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[Des-His1,Glu9] Glucagon 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Des-His1,Glu9] Glucagon110121-11-4GCGRGlucagon Receptorglucagondiabeteshyperglycemiablood glucoseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
[Des-His1,Glu9] Glucagon
目录号：
HY-P3608
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z