1. Anti-infection
    Metabolic Enzyme/Protease
  2. Parasite
    Drug Metabolite
  3. Desmethyl ferroquine

Desmethyl ferroquine (Synonyms: SSR97213)

目录号: HY-135847
产品使用指南

Desmethyl ferroquine (SSR97213) 是 Ferroquine 的主要活性代谢产物。Ferroquine 是一种抗疟剂。Desmethyl ferroquine 显著抑制对 Chloroquine 敏感的和耐 Chloroquine 的恶性疟原虫菌株 P. falciparum

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Desmethyl ferroquine Chemical Structure

Desmethyl ferroquine Chemical Structure

CAS No. : 903546-18-9

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Description

Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].

In Vitro

The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days[1].

Molecular Weight

411.66

Formula

C₂₂H₁₄ClFeN₃

CAS No.

903546-18-9

SMILES

CNCC12=C3[Fe+2]1456789([C-]%10C6=C7C8=C9%10)[C-]2(C4=C53)CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Desmethyl ferroquineSSR97213SSR 97213SSR-97213ParasiteDrug MetaboliteInhibitorinhibitorinhibit

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产品名称:
Desmethyl ferroquine
目录号:
HY-135847
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